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Deborah Elstein Selected Research

imiglucerase

7/2015Safety and efficacy results of switch from imiglucerase to velaglucerase alfa treatment in patients with type 1 Gaucher disease.
9/2014Management of Gaucher disease: enzyme replacement therapy.
7/2013Safety and efficacy of velaglucerase alfa replacement therapy for patients with type 1 Gaucher disease.
3/2013Safety and efficacy of velaglucerase alfa in Gaucher disease type 1 patients previously treated with imiglucerase.
1/2013Achievement of therapeutic goals with low-dose imiglucerase in Gaucher disease: a single-center experience.
1/2012Booster-effect with velaglucerase alfa in patients with Gaucher disease switched from long-term imiglucerase therapy: early Access Program results from Jerusalem.
6/2011Recent advances in treatment approaches to Gaucher disease.
1/2011Nonprecipitous changes upon withdrawal from imiglucerase for Gaucher disease because of a shortage in supply.
1/2009Review of the safety and efficacy of imiglucerase treatment of Gaucher disease.
10/2007Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

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Deborah Elstein Research Topics

Disease

86Gaucher Disease (Gaucher's Disease)
01/2018 - 01/2002
8Fabry Disease (Fabry's Disease)
01/2020 - 12/2006
7Thrombocytopenia (Thrombopenia)
04/2014 - 01/2002
6Pain (Aches)
07/2015 - 01/2002
5Lysosomal Storage Diseases (Lysosomal Storage Disease)
01/2018 - 11/2005
5Necrosis
10/2016 - 08/2003
5Parkinson Disease (Parkinson's Disease)
03/2015 - 02/2005
5Inflammation (Inflammations)
03/2010 - 01/2005
4Hemorrhage
10/2016 - 02/2004
4Osteoporosis
10/2016 - 01/2004
4Birth Weight (Birth Weights)
04/2014 - 10/2010
4Hypersensitivity (Allergy)
02/2013 - 01/2009
4Pulmonary Hypertension
06/2007 - 08/2003
3Osteonecrosis (Kienbock's Disease)
09/2014 - 08/2003
3Anemia
04/2014 - 01/2002
3Bone Diseases (Bone Disease)
01/2011 - 08/2007
2Renal Insufficiency (Renal Failure)
01/2020 - 01/2010
2Hepatomegaly
01/2018 - 05/2010
2Fatigue
07/2015 - 06/2012
2Tay-Sachs Disease
04/2015 - 01/2012
2Hypertension (High Blood Pressure)
04/2015 - 04/2007
2Ischemic Stroke
10/2014 - 11/2013
2Tremor (Tremors)
09/2014 - 05/2003
2Cognitive Dysfunction
09/2014 - 02/2005
2Missed Abortion
04/2014 - 10/2011
2Inborn Genetic Diseases (Disease, Hereditary)
10/2013 - 01/2012
2Proteinuria
09/2012 - 11/2005
2Chronic Disease (Chronic Diseases)
06/2012 - 02/2005
2Mucopolysaccharidosis II (Hunter Syndrome)
01/2012 - 09/2011
2Neoplasms (Cancer)
01/2011 - 10/2009
2Hypersplenism (Anemia, Splenic)
03/2010 - 01/2002
2Peripheral Nervous System Diseases (PNS Diseases)
10/2007 - 05/2003
2Lung Diseases (Lung Disease)
06/2007 - 08/2003
2Infections
02/2004 - 06/2002
1Metabolic Diseases (Metabolic Disease)
01/2018
1Liver Diseases (Liver Disease)
01/2018
1Splenomegaly
01/2018
1Postpartum Hemorrhage
10/2016
1Stillbirth
10/2016
1Aneuploidy (Aneuploid)
10/2015
1Clinical Deterioration
07/2015
1Gastroenteritis
01/2015
1Large Granular Lymphocytic Leukemia
12/2014
1Stroke (Strokes)
10/2014
1Premature Birth (Birth, Premature)
06/2014
1Fever (Fevers)
04/2014
1Perinatal Death
04/2014
1Myotonic Dystrophy (Dystrophia Myotonica)
10/2013
1Neurofibromatoses (Neurofibromatosis)
10/2013

Drug/Important Bio-Agent (IBA)

20Glucosylceramidase (Glucocerebrosidase)IBA
11/2017 - 01/2003
17EnzymesIBA
11/2017 - 07/2002
10imigluceraseFDA Link
07/2015 - 10/2007
8Glucosylceramides (Glucocerebrosides)IBA
01/2018 - 05/2003
7Biomarkers (Surrogate Marker)IBA
01/2020 - 05/2005
5LipidsIBA
01/2017 - 01/2002
5Pharmaceutical PreparationsIBA
07/2015 - 02/2005
5Calcitriol Receptors (Calcitriol Receptor)IBA
06/2014 - 11/2008
4Prostaglandins DIBA
10/2013 - 01/2011
4miglustat (Zavesca)FDA Link
10/2007 - 03/2002
3Hemoglobins (Hemoglobin)IBA
01/2018 - 01/2012
3Proteins (Proteins, Gene)FDA Link
11/2005 - 01/2003
2sphingosyl beta-glucosideIBA
01/2017 - 01/2013
2AcidsIBA
11/2016 - 11/2005
2AntibodiesIBA
07/2015 - 01/2009
2taliglucerase alfaIBA
01/2015 - 11/2011
2GalactosidasesIBA
10/2014 - 09/2012
2Lysergic Acid Diethylamide (LSD)IBA
01/2013 - 01/2012
2geranylgeraniol monophosphateIBA
10/2011 - 10/2010
2GlycolipidsIBA
06/2011 - 01/2005
2CeramidesIBA
06/2011 - 05/2008
2methyl 4-azidophenylacetimidate (APAI)IBA
01/2011 - 01/2010
2CytokinesIBA
12/2006 - 07/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2006 - 07/2005
2pro-brain natriuretic peptide (1-76)IBA
05/2005 - 01/2004
2C-Reactive ProteinIBA
05/2005 - 01/2005
2Brain Natriuretic Peptide (Natrecor)FDA Link
05/2005 - 01/2004
1AdiponectinIBA
01/2020
1Hormones (Hormone)IBA
01/2020
1Investigational DrugsIBA
01/2017
1ABO Blood-Group SystemIBA
10/2016
1Blood Group Antigens (Blood Groups)IBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2015
1Hexosaminidases (Hexosaminidase)IBA
04/2015
1Biological ProductsIBA
12/2014
1Messenger RNA (mRNA)IBA
10/2014
1GD3 ganglioside (GD(3))IBA
09/2014
1SynucleinsIBA
09/2014
1algluceraseFDA Link
09/2014
1AngiotensinogenIBA
11/2013
1Ambroxol (Mucosolvan)IBA
02/2013

Therapy/Procedure

45Enzyme Replacement Therapy
01/2018 - 01/2002
15Therapeutics
01/2017 - 03/2002
8Enzyme Therapy
03/2011 - 09/2002
7Splenectomy
02/2013 - 01/2002
6Cesarean Section (Caesarean Section)
04/2015 - 08/2005
4Anesthesia
04/2014 - 08/2005
4Arthroplasty
04/2014 - 12/2004
2Drug Tapering
06/2011 - 05/2003
1Fluid Therapy (Oral Rehydration Therapy)
01/2015
1Analgesia
04/2014